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Although BALB/c mice do not naturally develop AD (Mancuso et al., 2019), their genetically stable background makes them an excellent model for isolating the effects of genetic modifications, environmental factors, or therapeutic interventions on AD pathology (Balietti et al., 2023)

It also modulated gut microbiota composition, lowering the Firmicutes/Bacteroidetes ratio and improving intestinal barrier function by increasing expression of tight junction proteins such as ZO-1, occludin, and claudin-1

Researchers also found that when treating mice with GHK-Cu, they were able to protect the lungs from acute injury and were able to stop the filtration of inflammatory cells into the lungs

Acknowledgments This work was supported by the University of Zagreb, Zagreb, Croatia (Grant BM 099)

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Mira, R